A Comparison between the Effects of Losartan and Fosinopril, Captopril on the Excretion Rate of Urinary Albumin and the Clearance of Endogenous Creatinine in Elderly Hypertensive Patients 氯沙坦与福辛普利、卡托普利对老年高血压患者尿白蛋白排泄量和内生肌酐清除率的对比研究
With the development of DN, the serum level of TGF β significantly increased. The alteration of serum level of TGF β was positively correlated with urinary albumin clearance. 结论:在糖尿病肾病早期,患者血中TGFβ含量就已开始增多,而且随着糖尿病肾病的进展,患者血中TGFβ含量明显增加,同时血清TGFβ含量的变化与尿白蛋白排泄率成正相关。
Their indexes such as blood pressure, nutrient parameter ( blood lipids, hemoglobin, total plasma protein and plasma albumin), creatinine clearance rate ( Ccr) and KT/ V, and survival rate were detected before and after dialyses. 观察两组病人透析前后血压、营养性指标(包括血脂、血红蛋白、血浆总蛋白和白蛋白)、充分性指标(包括Ccr和KT/V)及生存率变化。
The urinary albumin excretion rate ( UAER), plasma α granule membrane protein 140 ( GMP 140), BUN, Bcr and creatinine clearance rate ( CCR) were measured before and after the treatment. 治疗前后检测尿蛋白排泄率(UAER)、血浆α颗粒膜蛋白(GMP140)、血尿素氮(BUN)、血肌酐(Bcr)和肌酐清除率(CCR)。
Easy method for separation and recovery of albumin and clearance of bilirubin from plasma 简便法分离回收血浆白蛋白并清除胆红素
The degree of binding between drug and albumin, the bioactivity and the clearance rate of drugs can also be analyzed by this method. 此种体外测定小鼠用药后血清活性的体内体外结合的实验方法,简便快速,可初步分析药物与血清蛋白的结合率以及估算其生物利用度和清除率。
Methods: Adopting random and double-blind controlled trial methods, several indexes were observed in terms of uric micro-amount albumin excretion rate, creatinine clearance, hemorheology and platelet function et al. 方法:采用随机双盲对照实验方法,观察尿微量白蛋白排泄率、内生肌酐清除率、血液流变学及血小板功能等指标。
Results After treatment, blood plasma albumin and 24 hours urine protein quantity were both improved significantly in the two groups, while there was no obvious change of serum creatinine and endogenous creatinine clearance rates. 结果2组治疗后血浆白蛋白及24h尿蛋白定量均显著改善,而血肌酐、内生肌酐清除率均无明显变化。
With time extending, the integrin β 1mRNA decreased gradually. Conclusion: 1. Albumin overload can cause rat renal function disorder. Came up with proteinuria, oliguria, creatinine clearance decreased, kidney index increased and followed by kidney injury. 2. 实验结论:1.白蛋白超负荷可以引起肾脏功能的紊乱,出现蛋白尿、少尿、肌酐清除率降低、肾脏指数增加等表现,进而引起肾脏损伤。